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Childhood Peanut Allergy May Be Linked to Skin Gene Mutation

peanutsChildhood Peanut Allergy May Be Linked to Skin Gene Mutation

Can a gene mutation in a child’s skin predict who will develop peanut allergies? Scientists at King's College in London believe it can. After measuring the exposure to peanut protein in household dust in the first 12 months of life, they found the dust had no effect on children who did not have a skin barrier defect from an FLG gene mutation. The study raises the possibility of being able to identify a group of children with FLG mutations through genetic testing in the future, and altering their environmental exposure to peanuts early in life to reduce the risk of developing a peanut allergy.

HealthDay logoBy Mary Elizabeth Dallas, HealthDay Reporter
HealthDay Oct. 24, 2014

FRIDAY, Oct. 24, 2014 (HealthDay News) — Infants with a specific skin gene mutation who are exposed to peanut protein in household dust may be more likely to develop a peanut allergy, according to a new study.

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New Book Highlights “Missing Microbes”

Dr. Martin BlaserCan the overuse of antibiotics also be related to the increase in asthma, celiac disease and allergies? Dr. Martin Blaser, director of the Human Microbiome Program at New York University believes so. “Besides aiding the rise of superbugs, excess consumption of these medications may be changing and in some cases devastating our helpful bacteria and contributing to changes in our metabolism and immune system,” he says in his new book, Missing Microbes: How the Overuse of Antibiotics Is Fueling Our Modern Plagues.


NYU Doctor Looks to Our Bacteria for Allergy Explanations

October 22nd, 2014
By Kristen Stewart

What if the hygiene hypothesis to explain the rise in allergies and asthma is all wrong?

That is just one of the interesting new ideas proposed by Dr. Martin Blaser, director of the Human Microbiome Program at NYU, in his book Missing Microbes: How the Overuse of Antibiotics Is Fueling Our Modern Plagues.

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New Epinephrine Study Shows Alarming Results

Jayden is allergic to peanuts
Jayden is allergic to peanuts and carries his epinephrine in a red pouch.

A Disappointing Reality: Many Families of Food-Allergic Kids Are Not Carrying Epinephrine

Doctors at Nationwide Children’s Hospital in Columbus, Ohio recently polled 35 families at their allergy clinic, and were shocked to find how many were not carrying epinephrine with them. This includes 29% of those who previously had to use it due to a bad allergic reaction. This article  gives some very helpful advice on how to remember to carry it everywhere and how to to get prescription reminders and discounts.

By David Stukus, MD

It is a well-known fact that epinephrine is the best treatment for anaphylactic reactions. Patients or their adult caregivers are urged to always keep their epinephrine auto-injectors close at hand. Epinephrine should be given as early as possible after a reaction begins.

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U.S. Study Details Anaphylaxis Fatalities

Science 2.0 logoMost of us think of food or bee stings as the leading cause of allergy-related sudden deaths in the U.S. But a recent analysis of death certificates found it was actually medications that were the cause, particularly among older people and African Americans.

Medications: The Leading Cause Of Allergy-Related Deaths

By News Staff
September 30th 2014 07:01 PM

An analysis of death certificates from 1999 to 2010 has found that medications are the leading cause of allergy-related sudden deaths in the U.S. The study in the Journal of Allergy and Clinical Immunology also found that the risk of fatal drug-induced allergic reactions was particularly high among older people and African-Americans and that such deaths increased significantly in the U.S. in recent years.

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Peanut allergy prevalence in US children continues to rise

shelled and unshelled peanutsResearchers at Project Viva, conducted by Harvard Vanguard Medical Associates in Massachusetts, confirmed what we all have been reading about in the news: peanut allergies in children continue to rise. The research was conducted between 1999 and 2002 and found the prevalence of peanut allergies in children ranges from 2-5%, higher than what was previously reported.

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