No person should be expected to be fully responsible for self-administration of an epinephrine auto-injector. Assistance during anaphylaxis is crucial.From allergicliving.com. Based on guidelines from NIAID and the Canadian Society of Allergy and Clinical Immunology.
During the ambulance ride, the person having the serious reaction should be lying down, with the legs raised (this improves blood flow). NIAID guidelines recommend the patient receive oxygen and IV fluid.
A person who had an emergency epinephrine shot must be taken to hospital for observation. During transport, IF symptoms have not improved within 10 to 15 minutes, a second auto-injection should be given.
In studies of those who have died of anaphylaxis, they did not receive an epinephrine injection, or they got it too late, after a reaction had progressed. In anaphylaxis, prompt use of the shot is always essential.