“When in doubt, just do it!” A recent study by Canadian researchers found the best possible outcomes for those experiencing anaphylaxis resulted when epinephrine was administered before the patient reached the hospital. With 3,500 participants, the study also found that administering steroids and antihistamines can have a negative effect on patient outcomes. Antihistamines are part of many treatment plans in a pre-hospital setting for managing anaphylaxis (such as in schools or at home). This is certainly something that should be addressed in the medical community since many treatment plans given to schools indicate that Benadryl should be administered first. Sadly, less than one-third of anaphylactic reactions in these 3,500 patients were treated with epinephrine before arriving at the hospital, while antihistamines were used in 46 percent of cases.
By News Wire
New study shows that pre-hospital treatment with epinephrine has the highest protective effect against uncontrolled allergic reaction
MONTREAL, QC (30 May 2019)
Treatment guidelines for managing anaphylaxis in children should be reassessed, according to a new Canadian study published in the Journal of Allergy and Clinical Immunology: In Practice.
Involving nearly 3,500 patients, it is the largest study to assess the clinical outcomes of pre-hospital treatment of anaphylaxis, including the use of epinephrine autoinjector, antihistamines (such as diphenhydramine known most commonly as its brand name Benadryl) and corticosteroids. Of the patients examined, 80 percent were children aged 1 to 17 years.